Tuesday, September 18, 2012

No such thing as pigs free of antibiotic-resistant bacteria


Researchers have found there is no difference in the presence of antibiotic-resistant bacteria between pigs raised conventionally and those raised under antibiotic-free programs.

The North Carolina team found Campylobacter coli in both pig farms and said it seems the antibiotic-resistant bacteria come from the environment so it doesn’t matter whether hog farmers try to raise their pigs without antibiotics.

This peer-reviewed research has been published on the internet at www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0044662 .

Dr. Siddhartha Thakur, assistant professor of population health and pathobiology, had previously found that antibiotic-resistant C. coli, a leading cause of foodborne illness in the United States, was present in both ABF-certified and conventionally raised pigs.

The pathogen was present in both groups in all facilities from breeding to processing.

Thakur wanted to determine whether the C. coli that he found in each group was genetically the same, in order to see if the presence or absence of antimicrobial usage had an effect on the pathogen’s genetic makeup.

The rise of antibiotic-resistant pathogens such as C. coli is a concern for the food animal industry. Some pig farms have switched to raising ABF pigs in an attempt to get away from the conditions that facilitated antibiotic resistance.

The hope is that once the selection pressure – in the form of antimicrobial use – on C. coli to retain antibiotic resistance decreases, the pathogen will lose its resistance.

Over several years, Thakur and Ph.D. student Macarena Quintana-Hayashi collected thousands of samples from pigs and their surrounding environments, and performed a genetic analysis on 200 representative isolates of C. coli, to see if these strains were similar.