A researcher at McMaster University in Hamilton has
discovered something that will knock out the gene that equips bacteria with its
ability to survive an attack by antibiotics.
The discovery holds promise for restoring the power of
antibiotics that have been rendered ineffective by antibiotic resistance.
Dr. Gerry Wright, a biochemistry professor, led the team
that found the gene knockout substance in a soil sample from Nova Scotia.
It knocks out NDM-1, a gene that Danish researchers have
identified as key to providing resistance to a broad range of antibiotics.
So far the research has provided positive results with mice,
but it’s still a long way from approvals for medical use.
The medical profession is, however, keenly interested
because so many bacteria that cause infections and diseases have become
resistant to almost all antibiotics.
The discovery also holds exciting potential for treating
animal and poultry diseases and infections.